Description: Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3. Target: Apoptosis, HDAC, Autophagy, Influenza Virus. Smiles: O=C1C=2C=3C(C(=O)N1CCCCCC(NO)=O)=CC=CC3C=CC2. References: Su GH, et al. Cancer Res, 2000, 60(12), 3137-3142.

Scriptaid is a histone deacetylase inhibitor that has an optimal concentration of 6-8 µM in a cell-based assay, is less toxic than trichostatin A, and works in a wide variety of biological systems. It induces cell cycle arrest in colon cancer cells in culture and inhibits tumor growth in vitro and in vivo. Scriptaid...