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L-838,417
Item number: Cay22007-1
L-838,417 is a partial agonist of alpha2-, alpha3-, and alpha5 subunit-containing GABAA receptors. It potentiates GABA-induced currents in LTK- cells expressing alpha2beta3gamma2, alpha3beta3gamma2, or alpha5beta3gamma2 subunit-containing GABAA receptors when used at a concentration of 100 nM. In vivo, L-838,417 (10...
| Keywords: | 3-(2,5-difluorophenyl)-7-(1,1-dimethylethyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine |
| Application: | alpha2/alpha3/alpha5 subunit-containing GABAA receptor partial agonist |
| CAS | 286456-42-6 |
| MW: | 399.4 D |
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