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Item number: Cay14871-1

KRN 633 is an ATP-competitive inhibitor of VEGFR kinase activity (IC50s = 170, 160, and 125 nM for VEGFR1, 2, and 3, respectively). At higher concentrations KRN 633 inhibits PDGFR-alpha and c-KIT with IC50 values of 0.97 and 4.3 µM, respectively, and is inactive towards a panel of 17 additional kinases. KRN 633...

Keywords:	N-[2-chloro-4-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl]-N'-propyl-urea
Application:	VEGFR inhibitor
CAS	286370-15-8
MW:	416.9 D

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