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Item number: Cay41715-1

DYRK1A inhibitor compound 11 is an inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A, IC50 = 0.4 nM). It is selective for DYRK1A over DYRK2, CDC-like kinase 1 (Clk1), Clk2, Clk3, cyclin-dependent kinase 2 (Cdk2), and glycogen synthase kinase 3beta (GSK3beta, IC50s = 19, 7.1, 9.4, 54,...

Keywords:	Dual-specificity Tyrosine Phosphorylation-regulated Kinase 1A Inhibitor Compound 11, DYRK1 Inhibitor 1, DYRK1-IN-1,...
Application:	DYRK1A inhibitor
CAS	2814486-79-6
MW:	240.3 D

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DYRK1-IN-1

Item number: TGM-T60334-100mg

Description: DYRK1-IN-1 is a highly selective and ligand-efficient DYRK1A inhibitor that inhibits DYRK1A phosphorylation activity with an IC50 value of 220 nM. It exhibits good permeability and cellular activity without P-glycoprotein liability, making it suitable for research on central nervous system penetrant...

CAS	2814486-79-6
MW:	240.26 D

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