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Item number: Cay19694-5

alpha-Hydroxyglutaric acid (2-HG, Cay-16374) is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases. Mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder. Recent studies have found that mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2,...

Keywords:	(2R)-Octyl-2-HG-d17, 2R-hydroxy-pentanedioic acid, 1-octyl-d17 ester
Application:	Cell-permeable D-2-HG derivative
CAS	2748638-78-8
MW:	277.4 D

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