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Item number: Cay27057-1

Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 µM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 µM). It is selective for these enzymes over DNA polymerase alpha and beta, as well as mitochondrial DNA polymerase gamma (Kis = 5.2, 81.7, and...

Keywords:	PMPApp, TFV-DP, diphosphoric acid, anhydride with [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid,...
Application:	HIV reverse transcriptase inhibitor, NRTI
CAS	2738719-07-6
MW:	493.2 D

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