3 products were found matching "273404-37-8"!
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Belnacasan
Item number: TGM-T6090-5mg
Description: Belnacasan (VX-765) is an orally active inhibitor of IL-converting enzyme/caspase-1. Target: Caspase. Smiles: CCO[C@@H]1OC(=O)C[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)c1ccc(N)c(Cl)c1)C(C)(C)C. References: Wannamaker W, et al....
| Keywords: | VX-765 |
| Application: | Targets caspase 1 [EC:3.4.22.36] (CASP1) |
| CAS | 273404-37-8 |
| MW: | 508.99 D |
From 31.00€
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VX-765
Item number: Cay28825-5
VX-765 is a prodrug form of the caspase-1 inhibitor VRT-043198. VX-765 (50, 100, and 200 mg/kg) inhibits LPS-induced increases in serum IL-1beta levels in mice. It also reduces oxazolone-induced ear edema and levels of IL-1beta, IL-18, and IFN-gamma in ear tissue in an oxazolone-sensitized mouse model of...
| Keywords: | Belnacasan, N-(4-amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-L-prolinamide |
| Application: | Caspase-1 inhibitor prodrug |
| CAS | 273404-37-8 |
| MW: | 509 D |
From 85.00€
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VX-765
Item number: LKT-V9228.1
NLRP3 inhibitor.
| Keywords: | VX765 |
| Application: | Interleukin-1 beta converting enzyme (caspase 1) inhibitor |
| CAS | 273404-37-8 |
| MW: | 509 D |
From 204.00€
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