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Reparixin L-lysine salt
Item number: TGM-T12705-10mg
Description: Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor. Target: CXCR. Smiles: NCCCC[C@H](N)C(O)=O.CC(C)Cc1ccc(cc1)[C@@H](C)C(=O)NS(C)(=O)=O. References: Moriconi A, et al. Design of noncompetitive interleukin-8 inhibitors acting on CXCR1...
| Keywords: | Repertaxin L-lysine salt |
| Application: | Noncompetitive allosteric CXCR1 / CXCR2 inhibitor |
| CAS | 266359-93-7 |
| MW: | 429.57 D |
From 39.00€
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Reparixin (L-Lysine salt)
Item number: Cay21492-1
Reparixin is a non-competitive allosteric inhibitor of the activation of CXCR1 and CXCR2 chemokine receptors by IL-8 (IC50s = 1 and 100 nM, respectively). It blocks a range of activities related to IL-8 signaling, including leukocyte recruitment (IC50 = 1 nM) and other inflammatory responses, without affecting...
| Keywords: | Repertaxin, (alphaR)-alpha-methyl-4-(2-methylpropyl)-N-(methylsulfonyl)benzeneacetamide, L-lysine |
| Application: | Noncompetitive allosteric CXCR1 / CXCR2 inhibitor |
| CAS | 266359-93-7 |
| MW: | 429.6 D |
From 35.00€
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