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Suzetrigine
Item number: TGM-T69552-10mg
Description: Suzetrigine(VX-548) is an orally active and specific NaV1.8 inhibitor. Suzetrigine has analgesic activity and can be used to study acute pain and neurotransmission. Target: Sodium Channel. Smiles: C(NC=1C=C(C(N)=O)N=CC1)(=O)[C@H]2[C@@H]([C@H](C)[C@@]([C@@](F)(F)F)(C)O2)C3=C(OC)C(F)=C(F)C=C3. References:...
| Keywords: | VX-548 |
| Application: | Targets voltage-gated sodium channel type X alpha (SCN10A, NAV1.8) |
| CAS | 2649467-58-1 |
| MW: | 473.39 D |
From 477.00€
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Suzetrigine
Item number: Cay40799-1
Suzetrigine is an inhibitor of voltage-gated sodium channel 1.8 (Nav1.8, IC50 = 0.7 nM for the human channel). It is selective for Nav1.8 over a panel of eight additional voltage-gated sodium channels (IC50s = >10,000 nM for all).Formal Name:...
| Keywords: | VX-548,... |
| Application: | Nav1.8 blocker, analgesic |
| CAS | 2649467-58-1 |
| MW: | 473.4 D |
From 367.00€
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