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Item number: TGM-T27478-100mg

Description: GSK3987 is an LXR ligand. GSK3987 recruits the steroid receptor coactivator-1 to human LXRalpha and LXRbeta with EC50s of 40 nM. Target: Liver X Receptor. Smiles: COc1ccc(NC2=C(C(=O)N(Cc3ccccc3)C2=O)c2ccccc2)cc1. References: Ranganathan PV, et al. Netrin-1-treated macrophages protect the kidney against...

Application:	LXRalpha / LXRbeta dual agonist
CAS	264206-85-1
MW:	384.43 D

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GSK3987

Item number: Cay30954-5

GSK3987 is a dual agonist of liver X receptor alpha (LXRalpha) and LXRbeta. It recruits steroid receptor coactivator 1 (SRC-1) to LXRalpha and LXRbeta in a ligand-sensing assay (LiSA, EC50s = 50 and 40 nM, respectively). GSK3987 is 50-fold selective for LXRalpha and LXRbeta over a panel of nuclear receptors and...

Keywords:	3-[(4-methoxyphenyl)amino]-4-phenyl-1-(phenylmethyl)-1H-pyrrole-2,5-dione
Application:	LXRalpha / LXRbeta dual agonist
CAS	264206-85-1
MW:	384.4 D

536.00€ *

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