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Item number: Cay28284-1

GI 254023X is an inhibitor of the metalloproteinase-disintegrin ADAM10 (IC50 = 5.3 nM). It is selective for ADAM10 over ADAM17, matrix metalloproteinase-1 (MMP-1), and MMP-3 (IC50s = 541, 108, and 187 nM, respectively), but also inhibits MMP-9 and MMP-13 (IC50s = 2.5 and 1.1 nM, respectively). GI 254023X inhibits...

Keywords:	GI 4023, SRI 028594,...
Application:	ADAM10 inhibitor
CAS	260264-93-5
MW:	391.5 D

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