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Item number: TGM-T6775-100mg

Description: BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator. Target: Guanylate cyclase. Smiles: Nc1nc(ncc1C1CC1)-c1nn(Cc2ccccc2F)c2ncccc12. References: Becker EM, et al. BMC Pharmacol. 2001, 1, 13.

Application:	Soluble guanylate cyclase activator
CAS	256376-24-6
MW:	360.39 D

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BAY 41-2272

Item number: Cay10057-5

Soluble guanylate cyclase (sGC), a receptor for nitric oxide (NO), is a heterodimer consisting of alpha and beta subunits, with the beta subunit featuring a heme-nitric oxide (H-NOX) binding domain. The binding of NO to H-NOX induces sGC to generate the second messenger cGMP. BAY 41-2272 is a pyrazolopyridine...

Keywords:	5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine
Application:	Soluble guanylate cyclase activator
CAS	256376-24-6
MW:	360.4 D

From 145.00€ *

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