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Item number: Cay22204-5

Emricasan is a pan-caspase inhibitor. Ex vivo, emricasan (10 mg/kg) prevents cold ischemia-warm reperfusion-induced sinusoidal endothelial cell (SEC) apoptosis and inhibits caspase-3 activation in rat liver by 55 and 94%, respectively. In vivo, emricasan reduces alanine aminotransferase (ALT) levels (ED50s = 95%....

Keywords:	IDN-6556, PF-03491390,...
Application:	Antiinflammatory, Caspase-1 inhibitor
CAS	254750-02-2
MW:	569.5 D

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