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Item number: Cay22204-5

Emricasan is a pan-caspase inhibitor. Ex vivo, emricasan (10 mg/kg) prevents cold ischemia-warm reperfusion-induced sinusoidal endothelial cell (SEC) apoptosis and inhibits caspase-3 activation in rat liver by 55 and 94%, respectively. In vivo, emricasan reduces alanine aminotransferase (ALT) levels (ED50s = 95%....

Keywords:	IDN-6556, PF-03491390,...
Application:	Antiinflammatory, Caspase-1 inhibitor
CAS	254750-02-2
MW:	569.5 D

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Emricasan

Item number: TGM-T6826-5mg

Description: Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties. Emricasan has anti-inflammatory and anti-apoptotic activity and can be used in the treatment of infections and liver failure, etc. Emricasan also inhibits Zika virus infections. Target: Caspase, Influenza Virus. Smiles:...

Keywords:	IDN-6556, PF 03491390
Application:	Targets caspase 1 [EC:3.4.22.36] (CASP1)
CAS	254750-02-2
MW:	569.5 D

From 38.00€ *

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