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(5Z)-7-Oxozeaenol
(5Z)-7-Oxozeaenol

Item number: Cay17459-5

(5Z)-7-Oxozeaenol is a resorcylic acid lactone fungal metabolite and an inhibitor of TGF-beta activated kinase 1 (TAK1, IC50 = 8.1 nM in the presence of TAK1-binding protein 1 (TAB1)). It is selective for TAK1 over MEK1 and MEKK1 (IC50s = 411 and 268 nM, respectively), as well as apoptosis signal-regulating kinase 1...
Keywords: FR148083, L-783,279, LL-Z 1640-2,...
Application: TAK1 inhibitor
CAS 253863-19-3
MW: 362.4 D
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