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Item number: Cay13122-1

CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 values of 10 and 6.7 nM, respectively. When tested against twenty different protein kinases, this inhibitor shows greater than 500-fold selectivity for GSK3. CHIR99021 activates glycogen synthesis in CHO-IR cells (EC50 = 0.763...

Keywords:	CT 99021,...
Application:	GSK3alpha and GSK3beta inhibitor
CAS	252917-06-9
MW:	465.3 D

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