3 products were found matching "252916-29-3"!
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Orantinib
Item number: TGM-T6184-100mg
Description: Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2 and does not suppresses EGFR. Target: Apoptosis, PDGFR, VEGFR, FGFR....
| Keywords: | SU6668, NSC 702827, TSU-68 |
| Application: | Tyrosine kinase inhibitor |
| CAS | 252916-29-3 |
| MW: | 310.35 D |
From 46.00€
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SU 6668
Item number: Cay13873-1
SU 6668 is an inhibitor of the receptor tyrosine kinases PDGFRbeta, VEGFR2, and FGFR1 (IC50 = 0.06, 2.4, and 3.0 µM, respectively) but not EGFR (IC50 >100 µM). Through these actions, SU 6668 suppresses tumor growth, blocks angiogenesis in tumors, and induces apoptosis of tumor vasculature and regression of...
| Keywords: | NSC 702827, Orantinib, TSU-68, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid |
| Application: | Tyrosine kinase inhibitor |
| CAS | 252916-29-3 |
| MW: | 310.4 D |
From 43.00€
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Orantinib
Item number: CDX-O0202-M025
Orantinib is an orally bioavailable receptor tyrosine kinase inhibitor. Orantinib binds to and inhibits the autophosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), and fibroblast growth factor receptor (FGFR), thereby inhibiting angiogenesis and...
| Keywords: | TSU68, SU 6668, NSC 702827, 5-[1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid |
| Application: | Receptor tyrosine kinase inhibitor |
| CAS | 252916-29-3 |
| MW: | 310.35 D |
From 337.00€
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