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(R)-AS-1
(R)-AS-1

Item number: Cay41673-1

(R)-AS-1 is a positive allosteric modulator of excitatory amino acid transporter 2 (EAAT2, EC50 = 11 nM in a glutamate uptake assay). It is selective for EAAT2 over EAAT1, EAAT3, and a panel of 30 other ion channels, transporters, receptors, and enzymes. (R)-AS-1 (60 and 90 mg/kg) increases spontaneous locomotor...
Keywords: alphaR-methyl-2,5-dioxo-N-(phenylmethyl)-1-pyrrolidineacetamide
Application: EAAT2 positive allosteric modulator
CAS 2506367-95-7
MW: 260.3 D
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