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Ferroptocide
Ferroptocide

Item number: Cay39005-1

Ferroptocide is an inhibitor of thioredoxin (Trx) and a derivative of pleuromutilin (Cay-19452). It inhibits Trx activity in ES-2 ovarian cancer cells when used at a concentration of 20 µM and is cytotoxic to ES-2 cells (IC50 = 1.6 µM). Ferroptocide (5 µM) induces ferroptosis in ES-2 cells, an effect that can be...
Keywords: (2S,3aS,4S,5R,7R,8S,8aS,9R)-octahydro-2,8a-dihydroxy-4,8,9-trimethyl-1-oxo-5-(2,3,5,8-tetrahydro-1,3-dioxo-2-phenyl-1H-[1,...
Application: Thioredoxin inhibitor
CAS 2505218-38-0
MW: 586.1 D
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