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Item number: Cay21254-5

JTC 801 is an antagonist of the nociceptin receptor (ORL1, Ki = 44.5 nM, IC50 = 94 nM) that is >100-, >100-, and >3-fold more selective for ORL1 over the related delta-, kappa-, and µ-opioid receptors, respectively. It demonstrates anti-nociceptive effects in acute pain models in mice upon oral administration at 1...

Keywords:	N-(4-amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]-benzamide, monohydrochloride
Application:	ORL1 antagonist
CAS	244218-51-7
MW:	448 D

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