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Resatorvid
Item number: TGM-TQ0181-100mg
Description: Resatorvid (TAK-242), a selective Toll-like receptor 4 (TLR4) inhibitor, binds directly to Cys747 to prevent TLR4-TIRAP interaction, thereby blocking downstream signaling. Resatorvid exhibits antitumor, anti-inflammatory, and neuroprotective activities. Target: Autophagy, TLR, Interleukin, TNF....
| Keywords: | TAK-242, CLI-095 |
| Application: | TLR4 adaptor binding inhibitor |
| CAS | 243984-11-4 |
| MW: | 361.82 D |
From 45.00€
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TAK-242
Item number: Cay13871-1
TAK-242 is an antagonist of toll-like receptor 4 (TLR4) with an IC50 value of 0.68 µM in a secreted alkaline phosphatase (SEAP) assay. It selectively binds to TLR4 over TLR1-3 and TLR5-10 when used at a concentration of 100 nM. TAK-242 (1 µM) prevents the interaction of TLR4 with its adaptor proteins TIRAP or TRAM...
| Keywords: | Resatorvid, 6R-[[(2-chloro-4-fluorophenyl)amino]sulfonyl]-1-cyclohexene-1-carboxylic acid, ethyl ester |
| Application: | TLR4 adaptor binding inhibitor |
| CAS | 243984-11-4 |
| MW: | 361.8 D |
From 98.00€
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