7 products were found matching "24280-93-1"!

Description: Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity. Target: Dehydrogenase, Antibacterial, Apoptosis, UGT, Antifungal, Antibiotic, Endogenous Metabolite. Smiles: CC1=C2C(=C(O)C(C/C=C(/CCC(O)=O)\C)=C1OC)C(=O)OC2. References:...

Mycophenolic acid is an immunosuppresive microbial metabolite that has been found in P. brevicompactum. It is also an active metabolite of mycophenolate mofetil (Cay-13988) that is formed via carboxylesterase 1 (CES1) and CES2. Mycophenolic acid is an inhibitor of IMP dehydrogenase (IMPDH) type I and type II (IC50s...

White to off-white solid. Soluble in DMSO, methanol or ethanol. Insoluble in water. Antibiotic, Shows antiviral, antifungal and antitumor properties, Immunosuppressive drug used to prevent rejection in organ transplantation, rheumatoid arthritis, and psoriasis, Potent reversible inhibitor of inosine-5'-monophosphate...

Mycophenolic acid (MPA) is used in combination with calcineurin inhibitors as maintenance immunosuppression for kidney transplant recipients. Solubility: Soluble in DMSO at 200mg/ml, soluble in ethanol at 30mg/ml, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10-100uM,...

Mycophenolic acid (CRM) (Cay-39477) is a certified reference material categorized as an immunosuppressive mycotoxin. Mycophenolic acid has been found as a contaminant in cereal grain dusts. Formulations containing mycophenolic acid have been used as immunosuppressive agents in the prevention of organ transplant...

Phthalide, PPARgamma agonist, IMPDH inhibitor, microtubule polymerization inhibitor.

Mycophenolic acid is a common Penicillium metabolite first reported in the 1930s as a possible mycotoxin. Re-investigation has shown mycophenolic acid to display a broad range of pharmacological activities including antitumor, antiviral, antifungal and antiprotozoan activities. However, it was the discovery that...