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Item number: TGM-T26632-100mg

Description: AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 µM.AnnH31 can be used as a probe to confirm the involvement of DYRK1A in cellular phosphorylation. Target: DYRK, MAO. Smiles: C(C#N)N1C=2C(C=3C1=C(C)N=CC3)=CC=C(OC)C2. References: Rüben K, et al....

CAS	241809-12-1
MW:	251.28 D

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DYRK1A/B Inhibitor AnnH31

Item number: AG-CR1-3650-C500

Off-white to tan solid. Soluble in DMSO. Potent selective membrane-permeable DYRK1A (IC50=81nM) and DYRK1B inhibitor. Off-target inhibition of CLK1 and slightly DYRK2 and HIPK2, Shows minimal inhibitory effects on monoamine oxidase A (MAO A) (IC50=3.2µg), with 40-fold selectivity for DYRK1A over MAO A,...

Keywords:	2-(7-Methoxy-1-methyl-9H-pyrido[3,4-b]indol-9-yl)acetonitrile, AnnH31
Application:	Potent selective membrane-permeable DYRK1A / DYRK1B inhibitor
CAS	241809-12-1
MW:	251,3 D

154.00€ *

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