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Item number: AG-CR1-3650-C500

Off-white to tan solid. Soluble in DMSO. Potent selective membrane-permeable DYRK1A (IC50=81nM) and DYRK1B inhibitor. Off-target inhibition of CLK1 and slightly DYRK2 and HIPK2, Shows minimal inhibitory effects on monoamine oxidase A (MAO A) (IC50=3.2µg), with 40-fold selectivity for DYRK1A over MAO A,...

Keywords:	2-(7-Methoxy-1-methyl-9H-pyrido[3,4-b]indol-9-yl)acetonitrile, AnnH31
Application:	Potent selective membrane-permeable DYRK1A / DYRK1B inhibitor
CAS	241809-12-1
MW:	251,3 D

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