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11-A-M
Item number: Cay39458-5
11-A-M is an ionizable cationic lipid. Lipid nanoparticles (LNPs) containing 11-A-M and encapsulating siRNA for the gene encoding GFP reduce its gene expression selectively in splenic T cells but not hepatocytes in mice that constitutively express GFP.Formal Name: tricyclo[3.3.1.13,7]decane-1-acetic acid,...
| Keywords: | tricyclo[3.3.1.13,7]decane-1-acetic acid,... |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2408140-60-1 |
| MW: | 702 D |
From 209.00€
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LNP Lipid-8
Item number: TGM-T84801-10mg
Description: LNP Lipid-8 (11-A-M), an ionizable lipid, is utilized in lipid nanoparticles (LNP) for siRNA delivery to T cells without ligand targeting. When loaded with GFP siRNA (siGFP), it significantly silences the GFP gene in a mouse model [1]. Target: Others. Smiles:...
| CAS | 2408140-60-1 |
| MW: | 702.02 D |
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