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BMS-502
Item number: TGM-T77761-100mg
Description: BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) alpha and zeta that induces immune responses in human and mouse T cells and blocks intracellular checkpoint signaling in T cells. BMS-502 stimulates immune responses in a dose-dependent manner and can be used to study immune-related...
| Application: | DGK-alpha/DGK-zeta/DGK-iota inhibitor |
| CAS | 2407854-18-4 |
| MW: | 516.5 D |
From 125.00€
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BMS 502
Item number: Cay39303-1
BMS 502 is an inhibitor of diacylglycerol kinase alpha (DGK-alpha), DGK-zeta, and DGK-iota (IC50s = 0.0046, 0.0021, and 0.0026 µM, respectively). It is selective for these DGKs over DGK-beta, DGK-gamma, and DGK-kappa (IC50s = 1, 0.68, and 4.6 µM, respectively). BMS 502 increases levels of IFN-gamma and...
| Keywords: | 8-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]-5,6-dihydro-5-methyl-7-nitro-6-oxo-1,5-naphthyridine-2-carbonitrile |
| Application: | DGK-alpha/DGK-zeta/DGK-iota inhibitor |
| CAS | 2407854-18-4 |
| MW: | 516.5 D |
From 36.00€
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