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CU-32
CU-32

Item number: TGM-T38328-10mg

Description: CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS, IC50= 0.45 µM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. It is also selective...
Application: cGAS inhibitor
CAS 2400954-16-5
MW: 371.13 D
From 198.00€ *
Review
CU-32
CU-32

Item number: Cay31029-1

CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS, IC50 = 0.45 µM). It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 (IRF3, Cay-22811) in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. It is also...
Keywords: methyl 4-amino-6-((4-iodophenyl)amino)-1,3,5-triazine-2-carboxylate
Application: cGAS inhibitor
CAS 2400954-16-5
MW: 371.1 D
From 111.00€ *
Review