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IMP-1710
Item number: TGM-T37591-100mg
Description: IMP-1710 is a selective UCH-L1 inhibitor with an IC50 value of 38 nM in a fluorescence polarization assay. Target: DUB. Smiles: C(=O)(N1C=2C(=C(C=CC2)C=3C=4C(NC3)=NC=C(C#C)C4)CC1)[C@H]5N(C#N)CCC5. References: Panyain, N., Godinat, A., Lanyon-Hogg, T., et al.Discovery of a potent and selective covalent...
| Application: | Clickable UCH-L1 inhibitor |
| CAS | 2383117-96-0 |
| MW: | 381.43 D |
From 291.00€
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IMP-1710
Item number: Cay31391-1
IMP-1710 is an inhibitor of ubiquitin C-terminal hydrolase L1 (UCH-L1, IC50 = 38 nM in a fluorescence polarization assay) that contains an alkyne moiety for use in click chemistry reactions. It is selective for UCH-L1 over a panel of 20 deubiquitinating enzymes at 1 µM. IMP-1710 inhibits TGF-beta1-induced...
| Keywords: | (2S)-2-[[4-(5-ethynyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-2,3-dihydro-1H-indol-1-yl]carbonyl]-1-pyrrolidinecarbonitrile |
| Application: | Clickable UCH-L1 inhibitor |
| CAS | 2383117-96-0 |
| MW: | 381.4 D |
From 130.00€
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