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Item number: TGM-T11583-100mg

Description: HWL-088 is a potent free fatty acid receptor 1 (FFA1/GPR40) agonist. HWL-088 significantly improves glucose tolerance in normal and diabetic models. Target: Others. Smiles: Cc1ccccc1-c1cccc(COc2ccc(OCC(O)=O)c(F)c2)c1. References: Li Z, et al. Discovery of HWL-088: A highly potent FFA1/GPR40 agonist...

CAS	2378617-96-8
MW:	366.38 D

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HWL-088

Item number: Cay30227-1

HWL-088 is an agonist of free fatty acid receptor 1 (FFAR1/GPR40) and peroxisome proliferator-activated receptor delta (PPARdelta). It induces calcium mobilization in CHO cells expressing human FFAR1/GPR40 (EC50 = 18.9 nM) and transactivation of PPARdelta in a reporter assay using HEK293 cells (EC50 = 570.9 nM)....

Keywords:	2-[2-fluoro-4-[(2'-methyl[1,1'-biphenyl]-3-yl)methoxy]phenoxy]-acetic acid
Application:	FFAR1(GPR40)/PPARdelta agonist
CAS	2378617-96-8
MW:	366.4 D

From 103.00€ *

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