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Item number: Cay41676-1

PTX80 is an antagonist of p62 (IC50 = 31.18 nM for the human receptor). It decreases the soluble fraction of p62 in MM.1S multiple myeloma cells when used at a concentration of 1.5 µM. PTX80 (200 nM) increases the levels of polyubiquitinated proteins in MM.1S cells. It induces apoptosis in MM.1S cells when used at a...

Keywords:	4,4'-((1E,1'E)-(1-((3-(dimethylamino)propyl)sulfonyl)-4-oxopiperidine-3,5-diylidene)bis(methaneylylidene))dibenzonitrile
Application:	p62 (SQSTM1) antagonist
CAS	2376297-69-5
MW:	474.6 D

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