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Item number: TGM-T7424-100mg

Description: NDI-091143 is a potent, high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), indirectly disrupting citrate binding via an unexpected mechanism of inhibition. Target: ATP Citrate Lyase. Smiles: COC(=O)c1cc(Cl)c(O)c(c1)S(=O)(=O)Nc1cc(c(F)cc1F)-c1ccccc1....

Application:	ACLY inhibitor
CAS	2375840-87-0
MW:	453.84 D

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NDI-091143

Item number: Cay36054-10

NDI-091143 is an allosteric inhibitor of ATP citrate lyase (ACL, Ki = 7 nM). It inhibits the production of ADP in a cell-free assay and oxaloacetate production in an enzyme-coupled assay (IC50s = 2.1 and 4.8 nM, respectively).Formal Name:...

Keywords:	3-chloro-5-[[(4,6-difluoro[1,1'-biphenyl]-3-yl)amino]sulfonyl]-4-hydroxy-benzoic acid, methyl ester
Application:	ACLY inhibitor
CAS	2375840-87-0
MW:	453.8 D

From 81.00€ *

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