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ALSTERPAULLONE
Item number: TGM-T7426-100mg
Description: Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec. Target: CDK, GSK-3, Apoptosis. Smiles: [O-][N+](=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1. References: Cui C , Wang Y , Wang Y , et al. Alsterpaullone, a Cyclin-Dependent Kinase...
| Application: | CDK inhibitor |
| CAS | 237430-03-4 |
| MW: | 293.28 D |
From 87.00€
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Alsterpaullone
Item number: Cay14428-1
Alsterpaullone is a derivative of kenpaullone (Cay-10010239), an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3beta (GSK3beta). With slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E,...
| Keywords: | 9-Nitropaullone, NSC 705701, 7,12-dihydro-9-nitro-indolo[3,2-d][1]benzazepin-6(5H)-one |
| Application: | CDK inhibitor, GSK-3beta inhibitor |
| CAS | 237430-03-4 |
| MW: | 293.3 D |
From 92.00€
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Alsterpaullone
Item number: AG-CR1-0036-M001
Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor, Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM), GSK-3beta (glycogen synthase kinase-3beta) inhibitor, Apoptosis inhibitor, Apoptosis inducer, Angiogenesis inhibitor.
| Keywords: | 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one |
| Application: | CDK inhibitor |
| CAS | 237430-03-4 |
| MW: | 293,3 D |
From 44.00€
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Alsterpaullone
Item number: LKT-A4577.1
Dark yellow powder. The most active paullone. It is a potent inhibitor of glycogen synthase kinase-3b and cyclin - dependent kinase 5/p25. It has been shown to induce apoptosis and promote loss in clonogenicity in the Jurkate cell line.
| Application: | Kinase inhbitor |
| CAS | 237430-03-4 |
| MW: | 293,28 D |
From 245.00€
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