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Item number: Cay41878-1

PROTAC CRBN degrader-1 is a proteolysis-targeting chimera (PROTAC) that contains VHL ligand 1 (Cay-21591) conjugated to the cereblon (CRBN) inhibitor pomalidomide (Cay-19877). It induces degradation of CRBN in HeLa cells with a half-maximal degradation concentration (DC50) value of 200 nM.Formal Name:...

Keywords:	PROTAC Cereblon Degrader-1, Proteolysis-targeting Chimera Cereblon Degrader-1, Proteolysis-targeting Chimera CRBN...
Application:	CRBN degradation driving PROTAC
CAS	2358775-70-7
MW:	1061.3 D

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PROTAC CRBN Degrader-1

Item number: TGM-T18604-5mg

Description: PROTAC CRBN Degrader-1 is a chemical compound consisting of a cereblon (CRBN) ligand binding group, a linker, and a von Hippel-Landau (VHL) binding group. It functions as a cereblon (CRBN) degrader[1]. Target: Others, PROTACs. Smiles: O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCNC(COCCCCCOCC...

CAS	2358775-70-7
MW:	1061.25 D

967.00€ *

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