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S1PR1 modulator 1
S1PR1 modulator 1

Item number: TGM-T12821-100mg

Description: S1PR1 modulator 1 is a selective inhibitor of S1PR1, with a pIC50 of 7.6. Target: LPL Receptor. Smiles: N(\CCC)=C\1/N(C(=O)\C(=C\C2=CC(C)=C(OC(C)=O)C=C2)\S1)C3=C(C)C=CC=C3. References: Bell M, et al. Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1). ACS Med...
Application: S1P1 agonist
CAS 2328109-05-1
MW: 408.51 D
From 60.00€ *
Review
CAY10739
CAY10739

Item number: Cay27837-5

CAY10739 is a soft-drug agonist of the sphingosine-1-phosphate receptor 1 (S1P1, IC50 = 25.12 nM in a beta-arrestin recruitment assay) that was designed to prevent systemic effects following topical application. It is selective for S1P1 over S1P2, S1P3, and S1P4 (IC50s = 1,000, >10,000, >10,000 nM, respectively, in...
Keywords: (2Z,5Z)-5-[[4-(acetyloxy)-3-methylphenyl]methylene]-3-(2-methylphenyl)-2-(propylimino)-4-thiazolidinone
Application: S1P1 agonist
CAS 2328109-05-1
MW: 408.5 D
From 132.00€ *
Review