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Item number: Cay70785-10

The peroxisome proliferator-activated receptor gamma (PPARgamma) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones. Thiazolidinediones are a group of structurally related synthetic PPARgamma agonists with antidiabetic actions in vivo. Rosiglitazone (BRL 49653) is...

Keywords:	2-chloro-5-nitrobenzanilide
Application:	Irreversible PPARgamma antagonist
CAS	22978-25-2
MW:	276.7 D

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GW9662

Item number: TGM-T2260-100mg

Description: GW9662 (TIMTEC-BB SBB006523) is a specific PPARgamma antagonist (IC50: 3.3 nM, in a cell-free assay), with 100 to 1000-fold functional selectivity for PPARgamma than PPARalpha/delta in cells. Target: PPAR. Smiles: [O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc1ccccc1. References: Leesnitzer LM, et al. Biochemistry,...

Keywords:	GW 9662, TIMTEC-BB SBB006523
Application:	Irreversible PPARgamma antagonist
CAS	22978-25-2
MW:	276.68 D

From 47.00€ *

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