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Item number: Cay41295-1

NVP-DKY709 is a degrader of Ikaros family zinc finger protein 2 (IKZF2) with a half-maximal degradation concentration (DC50) value of 4 nM. It is selective for IKZF2 over 8,656 other proteins, including IKZF1, IKZF3, and IKZF5, at 2.5 µM, but it does degrade IKZF4, which has the same zinc finger 2 beta-hairpin...

Keywords:	3-[1,3-dihydro-1-oxo-5-[1-(phenylmethyl)-4-piperidinyl]-2H-isoindol-2-yl]-2,6-piperidinedione
Application:	IKZF2 degrader
CAS	2291360-73-9
MW:	417.5 D

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NVP-DKY709

Item number: TGM-T9806-100mg

Description: NVP-DKY709 is a potent inhibitor of IKZF2 for the treatment of cancers. Target: Others. Smiles: O=C1C=2C(CN1C3C(=O)NC(=O)CC3)=CC(=CC2)C4CCN(CC5=CC=CC=C5)CC4. References: Simone BONAZZI, et al. Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione...

CAS	2291360-73-9
MW:	417.5 D

From 97.00€ *

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Review

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