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TAK-779
TAK-779

Item number: TGM-T7499-100mg

Description: TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3). Target: CXCR, HIV Protease, CCR. Smiles: [Cl-].Cc1ccc(cc1)-c1ccc2CCCC(=Cc2c1)C(=O)Nc1ccc(C[N+](C)(C)C2CCOCC2)cc1. References: Suzaki Y , Hamada K , Nomi T , et al. A small-molecule...
Keywords: Takeda 779
Application: CCR5 / CCR2b / CXCR3 antagonist
CAS 229005-80-5
MW: 531.13 D
From 40.00€ *
Review
TAK-779
TAK-779

Item number: Cay26744-1

TAK-779 is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3). It inhibits CCR5 and CXCR3 (IC50s = 236 and 369 nM, respectively, for mouse recombinant receptors expressed in 2B4 T cells) and CCR5 and CCR2b (IC50s = 1.4 and 27 nM, respectively, for human recombinant receptors...
Keywords: N-[[4-[[[6,7-dihydro-2-(4-methylphenyl)-5H-benzocyclohepten-8-yl]carbonyl]amino]phenyl]methyl]tetrahydro-N,N-dimethyl-2H-p...
Application: CCR5 / CCR2b / CXCR3 antagonist
CAS 229005-80-5
MW: 531.1 D
From 55.00€ *
Review