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MYCi975
Item number: TGM-T12133-10mg
Description: MYCi975 (NUCC-0200975) is an orally active MYC inhibitor. Target: c-Myc. Smiles: O(CC1=CC=C(Cl)C=C1)C2=C(C(O)=C(C=C2)C3=CC(C(F)(F)F)=NN3C)C4=CC(C(F)(F)F)=C(Cl)C=C4. References: Han H, et al. Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy. Cancer Cell. 2019 Nov...
| Keywords: | NUCC-0200975 |
| Application: | Myc-MAX protein-protein interaction inhibitor |
| CAS | 2289691-01-4 |
| MW: | 561.3 D |
From 126.00€
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MYCi975
Item number: Cay39622-10
MYCi975 is an inhibitor of the protein-protein interaction between Myc and Myc-associated factor X (MAX). It binds to Myc (Kd = 2.75 µM) and increases GSK3beta-mediated Myc phosphorylation in a cell-free assay. MYCi975 (5 and 10 µM) decreases the viability of MyC-CaP and LNCaP prostate cancer cells. It induces...
| Keywords: | NUCC-0200975,... |
| Application: | Myc-MAX protein-protein interaction inhibitor |
| CAS | 2289691-01-4 |
| MW: | 561.3 D |
From 239.00€
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