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Dooku1
Dooku1

Item number: TGM-T11076-100mg

Description: Dooku1 is an analog of Yoda1 and a selective antagonist of endogenous Piezo1 channels. Dooku1 inhibits Ca2+ entry induced by 2µMYoda1 with IC50 values of 1.3µM (in HEK 293 cells) and 1.5µM (in HUVEC). Dooku1 inhibits Yoda1-induced aortic relaxation. Target: Others. Smiles:...
CAS 2253744-54-4
MW: 326.2 D
From 40.00€ *
Review
Dooku1
Dooku1

Item number: Cay39161-10

Dooku1 is an antagonist of yoda1-activated Piezo1 ion channels (IC50 = 1.3 µM in HEK293 cells expressing the human receptor). It is selective for Piezo1 activated by yoda1 (Cay-21904) over constituitively active Piezo1, transient receptor potential vanilloid 4 (TRPV4), and transient receptor potential canonical 4...
Keywords: 2-[[(2,6-dichlorophenyl)methyl]thio]-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole
Application: Yoda1-activated Piezo1 antagonist
CAS 2253744-54-4
MW: 326.2 D
From 133.00€ *
Review