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Item number: Cay38790-1

B-973B is an allosteric agonist and positive allosteric modulator (ago-PAM) of alpha7 nicotinic acetylcholine receptors (nAChRs). It enhances ACh-induced activation in a two-electrode voltage-clamp assay using Xenopus oocytes expressing the human alpha7 nAChR when used at a concentration of 10 µM. B-973B (10 mg/kg)...

Keywords:	(-)-(S)-B-973B, 3,4-difluoro-N-[(1S)-1-[6-[4-(2-pyridinyl)-1-piperazinyl]-2-pyrazinyl]ethyl]-benzenepropanamide
Application:	alpha7 nAChR ago-PAM (allosteric agonist / positive allosteric modulator)
CAS	2244989-34-0
MW:	452.5 D

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