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(-)-(S)-B-973B
Item number: TGM-T17300-10mg
Description: (-)-(S)-B-973B is an effective allosteric agonist and positive allosteric modulator of alpha7 nAChR. Target: AChR. Smiles: C[C@H](NC(=O)CCc1ccc(F)c(F)c1)c1cncc(n1)N1CCN(CC1)c1ccccn1. References: Garai S, et al. B-973, a Novel alpha7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological...
| Application: | alpha7 nAChR ago-PAM (allosteric agonist / positive allosteric modulator) |
| CAS | 2244989-34-0 |
| MW: | 452.5 D |
From 45.00€
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B-973B
Item number: Cay38790-1
B-973B is an allosteric agonist and positive allosteric modulator (ago-PAM) of alpha7 nicotinic acetylcholine receptors (nAChRs). It enhances ACh-induced activation in a two-electrode voltage-clamp assay using Xenopus oocytes expressing the human alpha7 nAChR when used at a concentration of 10 µM. B-973B (10 mg/kg)...
| Keywords: | (-)-(S)-B-973B, 3,4-difluoro-N-[(1S)-1-[6-[4-(2-pyridinyl)-1-piperazinyl]-2-pyrazinyl]ethyl]-benzenepropanamide |
| Application: | alpha7 nAChR ago-PAM (allosteric agonist / positive allosteric modulator) |
| CAS | 2244989-34-0 |
| MW: | 452.5 D |
From 47.00€
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