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AZD 4604
AZD 4604

Item number: Cay39890-10

AZD 4604 is a JAK1 inhibitor (IC50 = 0.54 nM). It is selective for JAK1 over JAK2 and JAK3 (IC50s = 686 and >10,000 nM, respectively), as well as tyrosine kinase 2 (TYK2, IC50 = 657 nM). AZD 4604 inhibits IL-4- or IL-13-induced phosphorylation of STAT6 in U937 cells (IC50s = 24 and 34 nM, respectively). In vivo, AZD...
Keywords: Londamocitinib,...
Application: JAK1 inhibitor
CAS 2241039-81-4
MW: 599.7 D
From 35.00€ *
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Londamocitinib
Londamocitinib

Item number: TGM-T11706-100mg

Description: Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity. Target: JAK. Smiles: COC[C@@H](N1CCN(C)CC1)C(=O)Nc1cccc2c(c[nH]c12)-c1nc(Nc2cccc(c2F)S(C)(=O)=O)ncc1F. References: NILSSON, Karl, Magnus, et al. Jak1 selective inhibitors. WO2018134213A1.
Keywords: AZD4604
CAS 2241039-81-4
MW: 599.65 D
From 187.00€ *
Review