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Item number: TGM-T84759-10mg

Description: mRNA-Encapsulating Lipid Excipient 1 (Compound 2), a thiocarbamate-based ionizable lipid, serves as an excipient in the formulation of mRNA-encapsulating lipid nanoparticles [1]. Target: Others. Smiles: N(C(SCCCN(C)C)=O)(CCCC(OC(CCCCCCC)CCCCCCC)=O)CCCC(OC(CCCCCCC)CCCCCCC)=O

Keywords:	ATX-100, ATX 100, ATX100
CAS	2230647-37-5
MW:	755.23 D

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ATX-100

Item number: Cay36935-1

ATX-100 is an ionizable cationic lipid (pKa = 6.38). It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA. Intravenous administration of LNPs containing ATX-100 and encapsulating Factor VII siRNA decrease Factor VII blood levels in mice.Formal Name:...

Keywords:	4,4'-[[[[3-(dimethylamino)propyl]thio]carbonyl]imino]bis-butanoic acid, 1,1'-bis(1-heptyloctyl) ester
Application:	Cationic ionizable lipid
CAS	2230647-37-5
MW:	755.2 D

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