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Item number: TGM-T39716-5mg

Description: Mutant IDH1-IN-6 is an orally active compound that effectively inhibits mutant isocitrate dehydrogenase (IDH) enzymes. It demonstrates potency and selectivity, with IC50 values of 6.27, 3.71, 36.9, and 11.5 nM for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutants, respectively. Notably, Mutant...

Keywords:	Mutant IDH1-IN-6
Application:	Targets isocitrate dehydrogenase [EC:1.1.1.42] (IDH1, IDH2, icd)
CAS	2230263-60-0
MW:	504.635 D

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