2 products were found matching "2225819-06-5"!

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Item number: TGM-T14501-100mg

Description: BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity. Target: Dehydrogenase, DNA/RNA Synthesis. Smiles:...

Application:	DHODH inhibitor
CAS	2225819-06-5
MW:	520.84 D

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BAY-2402234

Item number: Cay33259-1

BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 1.2 nM). It induces upregulation of the cell differentiation marker CD11b in MOLM-13 and HEL acute myeloid leukemia (AML) cells (EC50s = 3.16 and 0.96 nM, respectively) and inhibits the proliferation of nine leukemia cell lines (IC50s =...

Keywords:	N-(2-chloro-6-fluorophenyl)-4-[4-ethyl-4,5-dihydro-3-(hydroxymethyl)-5-oxo-1H-1,2,4-triazol-1-yl]-5-fluoro-2-[(1S)-2,2,2-t...
Application:	DHODH inhibitor
CAS	2225819-06-5
MW:	520.8 D

From 130.00€ *

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