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Item number: Cay10954-10

1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over...

Keywords:	1-Naphthyl-PP1, PP1 Analog, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS	221243-82-9
MW:	317.4 D

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1-Naphthyl PP1

Item number: TGM-T3935-100mg

Description: 1-Naphthyl PP1 (1-NA-PP 1) is a selective Src inhibitor, targeting v-Src and c-Fyn, c-Abl, CDK2, and CAMK II with IC50 values of 1.0, 0.6, 0.6, 18, and 22 µM, respectively. Target: Src. Smiles: CC(C)(C)n1nc(-c2cccc3ccccc23)c2c(N)ncnc12. References: Tandon M, et al. New pyrazolopyrimidine inhibitors of...

Keywords:	1-NA-PP 1
CAS	221243-82-9
MW:	317.39 D

From 32.00€ *

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