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Item number: Cay39741-1

Orforglipron is a nonpeptide agonist of the glucagon-like peptide 1 receptor (GLP-1R). It induces cAMP accumulation in HEK293 cells expressing human GLP-1R (EC50 = 3.05 nM) and is selective for GLP-1R over the glucagon receptor (GCGR), gastric inhibitory polypeptide (GIP) receptor, and GLP-2R at 100 nM. Orforglipron...

Keywords:	LY3502970, OWL833,...
Application:	Nonpeptide GLP-1R agonist, hypoglycemic agent
CAS	2212020-52-3
MW:	883 D

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