3 products were found matching "220991-20-8"!
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Lumiracoxib
Item number: TGM-T6574-10mg
Description: Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 µM and 0.06 µM, exhibits 515-fold selectivity over COX-1. Phase 4. Target: COX. Smiles: N(C1=C(CC(O)=O)C=C(C)C=C1)C2=C(Cl)C=CC=C2F. References: Esser R, et al. Br J Pharmacol, 2005, 144(4), 538-550.
| Keywords: | COX-189, Prexige |
| Application: | Targets prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1] (PTGS2, COX2) |
| CAS | 220991-20-8 |
| MW: | 293.72 D |
From 31.00€
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Lumiracoxib
Item number: LKT-L8248.100
NSAID, COX-2 inhibitor.
| Keywords: | 2-[(2-Chloro-6-fluorophenyl)amino]-5-methylbenzeneacetic acid |
| CAS | 220991-20-8 |
| MW: | 293,72 D |
From 94.00€
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Lumiracoxib
Item number: Cay27645-50
Lumiracoxib is a selective inhibitor of COX-2 with IC50 values of 0.13 and 67 µM for COX-2 and COX-1, respectively, in isolated human whole blood. It reduces increases in the levels of prostaglandin E2 (PGE2, Cay-14010) induced by IL-1beta in human dermal fibroblasts (IC50 = 0.14 µM), as well as in LPS-stimulated...
| Keywords: | COX 189, 2-[(2-chloro-6-fluorophenyl)amino]-5-methyl-benzeneacetic acid |
| Application: | Selective COX-2 inhibitor |
| CAS | 220991-20-8 |
| MW: | 293.7 D |
From 44.00€
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