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ML-211
Item number: TGM-T8974-100mg
Description: ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and LYPLA2 (IC50 = 30 nM). Target: Others. Smiles: C(O)(C1=NN(C(=O)N2CCC(C(C)(C)C)CC2)N=C1)(C3=CC=CC=C3)C4=CC=CC=C4. References: Adibekian A , Martin B R , Chang J W , et al. Characterization of a Selective, Reversible Inhibitor of...
| Application: | LYPLA1 / LYPLA2 inhibitor |
| CAS | 2205032-89-7 |
| MW: | 418.53 D |
From 122.00€
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ML-211
Item number: Cay17630-1
Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas. Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling. ML-211 is a carbamate-based...
| Keywords: | [4-(1,1-dimethylethyl)-1-piperidinyl][4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl]-methanone |
| Application: | LYPLA1 / LYPLA2 inhibitor |
| CAS | 2205032-89-7 |
| MW: | 418.5 D |
From 52.00€
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