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BX 471
BX 471

Item number: Cay18503-1

The CC chemokine receptor-1 (CCR1), whose ligands include macrophage inflammatory protein-1alpha (MIP-1alpha), RANTES, and monocyte chemotactic protein-3 (MCP-3), has a central role in leukocyte trafficking and is highly expressed in certain autoimmune diseases. BX 471 is a nonpeptide CCR1 antagonist that has been...
Keywords: N-[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl]-2-oxoethoxy]phenyl]-urea
Application: CCR1 antagonist
CAS 217645-70-0
MW: 434.9 D
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