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Item number: TGM-T13336-100mg

Description: VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity. Target: Epigenetic Reader Domain, Histone Methyltransferase, Apoptosis. Smiles:...

Application:	Menin-MLL1 fusion protein interaction inhibitor
CAS	2169916-18-9
MW:	630.82 D

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VTP-50469

Item number: Cay40759-10

VTP-50469 is an inhibitor of the protein-protein interaction between menin and mixed lineage leukemia 1 (MLL1) fusion proteins (Ki = 0.104 nM). It selectively inhibits the growth of ten leukemia cell lines expressing MLL1 fusion proteins (IC50s = 13-37 nM) over HL-60 , K562, and Reh leukemia cells expressing...

Keywords:	5-fluoro-N,N-bis(1-methylethyl)-2-[[4-[7-[[trans-4-[(methylsulfonyl)amino]cyclohexyl]methyl]-2,7-diazaspiro[3.5]non-2-yl]-...
Application:	Menin-MLL1 fusion protein interaction inhibitor
CAS	2169916-18-9
MW:	630.8 D

From 285.00€ *

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