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Item number: TGM-T9542-100mg

Description: NS3861 is an agonist of nicotinic acetylcholine receptors (nAChRs) that binds with high affinity to heteromeric alpha3beta4 and alpha4beta2 nAChRs, displaying beta-subunit preference and no activation at alpha4-containing receptors. The maximal efficacy of NS3861 depends on the ligand-binding domain,...

Application:	Neuronal nAChR agonist
CAS	216853-59-7
MW:	284.22 D

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NS 3861

Item number: Cay37406-10

NS 3861 is a neuronal nicotinic acetylcholine receptor (nAChR) agonist. It induces inward currents in patch-clamp assays using X. laevis oocytes expressing recombinant human alpha3beta2- or alpha3beta4 subunit-containing nAChR receptors (EC50s = 1.6 and 1 µM, respectively). In vivo, NS 3861 (0.1 mg/kg) increases the...

Keywords:	3-(3-bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene
Application:	Neuronal nAChR agonist
CAS	216853-59-7
MW:	284.2 D

From 136.00€ *

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