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CU-CPT-9a
CU-CPT-9a

Item number: TGM-T7317-100mg

Description: CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-. Target: TLR. Smiles: COc1ccc2c(ccnc2c1)-c1ccc(O)c(C)c1. References: Zhang S , Hu Z , Tanji H , et al. Small-molecule inhibition of TLR8 through...
Application: TLR8 antagonist
CAS 2165340-32-7
MW: 265.31 D
From 34.00€ *
Review
CU-CPT9a
CU-CPT9a

Item number: Cay28722-1

CU-CPT9a is an antagonist of toll-like receptor 8 (TLR8). It inhibits activation of NF-kappaB induced by the TLR8 agonist R-848 (Cay-14806) in TLR8-overexpressing HEK-Blue cells (IC50 = 0.5 nM). CU-CPT9a reverses R-848-induced increases in NF-kappaB p65, IRAK-4, and TRAF3 protein levels in HEK-Blue cells.Formal...
Keywords: 4-(7-methoxy-4-quinolinyl)-2-methyl-phenol
Application: TLR8 antagonist
CAS 2165340-32-7
MW: 265.3 D
From 43.00€ *
Review